Androgens (including testosterone) are natural or synthetic steroid hormones that give men their 'male' characteristics.
Medications used in the treatment of epileptic seizures.
Testosterone is weakly bound to albumin (a carrier protein in the body). In this form, testosterone can detach from albumin and increase the level of biologically active testosterone.
CVD is a general term that describes a disease of the heart or blood vessels.
Chronic disease is a health condition or disease that is persistent in nature or otherwise long-lasting in its effects and often requires medical attention.
The presence of two or more medical conditions or diseases.
Coronary heart disease is where the blood vessels supplying the heart are narrowed or blocked, caused by a build up of fatty substances called plaque within the artery wall.
The endocrine system is made up of glands that make hormones which regulate normal bodily functions.
ED is defined as the inability to achieve or maintain a rigid penile erection suitable for satisfactory sexual intercourse.
FSH is one of the gonadotrophic hormones; hormones essential to pubertal development and the function of women’s ovaries and men’s testes.
Testosterone in the body is free (not attached to proteins), also referred to as bioavailable testosterone. This is testosterone that is easily used by your body.
Controlling blood glucose (sugar) levels.
High levels of lipids (or fats) in the blood, most noticeably low-density lipoprotein cholesterol (LDL-C), and triglycerides.
High blood pressure.
Low levels of testosterone in the blood (<8nmol/L), accompanying clinical symptoms of hypogonadism, such as low libido.
Referring to the communication between the hypothalamus, pituitary glands, and the gonads (reproductive organs, testes and ovaries).
A region in the brain responsible for keeping the body in a stable state, a process also known as homeostasis.
An immunoassay is a test that measures the concentration of substances (like testosterone) in the blood or other bodily tissues and fluids.
Leydig cells are found in the testes and produce testosterone stimulated by the luteinizing hormone.
The levels and proportion of different lipids (fats) in the blood.
Lipids, are also known as fats.
Luteinising hormone is produced and released by cells in the pituitary gland. In men, it stimulates the testes to make testosterone.
Mass spectrometry, also referred to as mass spectroscopy, is a technique by which chemical substances are identified by the sorting of gaseous ions in electric and magnetic fields according to their mass-to-charge ratios.
When someone has a combination of diabetes, high blood pressure, and obesity.
A class of medications that work in the brain to produce a variety of effects, such as relief of pain.
Sits at the base of the brain and is responsible for producing hormones to carry out important bodily functions, such as testosterone production in the testes.
Sex hormone-binding globulin is a protein made by the liver that transports hormones, specifically testosterone and estradiol.
Occurs when the immune system is constantly defending the body, creating high levels of inflammation throughout the body for an extended duration.
The internal organs of the body, including the lungs, the heart, and the organs of the digestive, excretory, reproductive, and circulatory systems.